Sheffield United boss Paul Heckingbottom said his promotion chasers were 'good value' for their hard-fought win at Bloomfield Road.
Goals from Sander Berge and James McAtee ensured the Blades kept the pressure on Championship leaders Burnley.
Norwegian midfielder Berge put Blades ahead with a close range finish in the first half and Manchester City loanee James McAtee added a superb solo goal to make it 2-0 just after the break.
Norwegian midfielder Sander Berge opened the scoring for Sheffield United on 18 minutes
Marvin Ekpiteta pulled one back to give Blackpool hope but Blades held out for their eighth win in nine games to bring them level on 50 points with Burnley who visit Stoke on Friday night.
Heckingbottom said: 'I'm really pleased with the way we defended and the bravery we showed side to take the ball under pressure
'We scored two good goals and looked comfortable. We could have donecbetter with their goal but after that, to a man, we defended very well and were good value for the win.'
Berge produced a composed finish after good work by Illman Ndiaye who cut the ball back
The Blades are certainly loving life on the road this season. This was their eighth away, win and they have conceded fewer goals than any other side in the division on their travels.
Blackpool made a positive start with Sonny Carey firing just wide, Ian Poveda seeing a scorching 25-yard drive tipped onto the bar by Wes Foderingham and Jerry Yates sending a shot on the turn wide.
But the Blades weathered the early storm and almost took the lead with their first serious attack when Anel Ahmedhodzic had a close range shot clawed round by Dan Grimshaw.
Manchester City loanee James McAtee then doubled the lead for the visitors on 49 minutes
They didn't have to wait long for a goal however with Berge producing a composed finish after 18 minutes following good work by Illman Ndiaye, who cut the ball back for the Norwegian.
McAtee put Blades two-up from a swift counter-attack soon after half-when he ran 80 yards before sliding his shot past Grimshaw.
Six minutes later the Seasiders pulled one back when defender Marvin Ekpiteta bundled the ball in after Gary Madine had headed a corner back across the goal mouth.
Marvin Ekpiteta's swift reply was not enough to inspire Blackpool to a positive result at home
And the Blades needed a last-gasp save from keeper Wes Foderingham to ensure they took all three points.
Seasiders boss Michael Appleton said: 'We've come up against a top side - they and Burnley are running away with it at the top.
'We showed spirit and togetherness and some quality - but not enough quality. I'm angry and frustrated at the easy way we allowed them to score the second goal.'